1、Presented by:2024 Longevity SummitJoseph Maroon,MD,FACSClinical Professor and Vice Chairman of the Department of Neurological SurgeryUniv of Pittsburgh Medical CenterHow to Attain Peak Performance at Any AgeDr.Joseph MaroonLongevity SummitJanuary 26,2024Topics Success,failure,and how a run around a
2、high school track saved my life Stress and the mind/body connection The best antidepressant Peak performance at any ageThe foundation is crackingThe windows are cloudyThe water is leakingThe roof is threadbareHow to Die young As Late As PossibleFirst 15 Years!Day”JobBrain tumorSecond 15 Years“All th
3、ings must suffer,go dark and perish before they can live again”“The life of every man is a diary in which he means to write one story,and writes another;His humblest hour is when he compares the volume as it is with what he vowed to make it.”British author Sir James BarrieMind-Body ConnectionPsychon
4、euroimmunologyWe Need StressStress Neurotransmitter loss DepressionHormone The Secret to a Balanced Life!RelationshipsSpirituality WorkPhysicalSpirituality RelationshipsWorkPhysical“My Square”The“run”that saved my life“Cmon,Joe,”he said.“Itll be good for you.”“Tin Man”TriathlonSwim 1/2 mile,bike 15
5、miles,Run 6.2 miles Increased my BDNFNeuronogenesisSynaptogenesisBrain plasticityEnhanced neurotransmittersSerotoninAcetylcholineDopamineNorepinephrineAnandamideExercise and the BrainLowers stress-induced cortisolRewires the brainRegular physical exercise:The Best Antidepressantand Anxiolytic How th
6、e Body Heals the Brain“Exercise is free,rarely induces side effects and can muffle existing feelings of anxiety and depression,or even prevent their occurrence in the first place.”1993 20031996 2008 1999 20102001 2013Muncie 70.3,2016,2017,2019,2020,2021,2022https:/www.florence- Oxygen-A RenaissanceT