EffeMIX® HappyCalm - 舒缓情绪护肤全流程.pdf

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1、EffeMIX-HappyCalmAng GaoShanghai CoachchemSeoul2ndJuly 2025Emotional Soothing Skincare in Full Signaling PathwaysLots of signaling pathways:TRPV1:PainNF-B:InflammatoryHistamine H1:RednessGABA and-endorphin:Soothing I just need ONE thing to solve it!EffeMIX-HappyCalmCalmness and Pain Relief（Inhibits

2、TRPV1 receptor）Piper MethysticumAnti-inflammatory（Inhibits NF-B）Silybum MarianumRedness Reduction（Inhibits histamine H1 receptor）Avena SativaEmotional Soothing（Regulates GABA and-endorphin）Piper MethysticumSilybum MarianumAvengers Assemble！检测结果来自第三方检测机构EffeMIX-HappyCalmInhibits TRPV1UV,scratching,co

3、ld,heat,chemical irritation,pollutantsA-、A-、C-type Skin Sensory Nerve FibersPain,Redness,Swelling,Burning,Stinging,ItchingActivate TRPV1 ReceptorsThe data is from a testing report conducted by a third-party testing institutionTRPV1 expression decrease(%)tert-butylcyclohexanolEffeMIX-HappyCalm Signif

4、icantly inhibits TRPV1EffeMIX-HappyCalmInhibits NF-B：IL-1The data is from a testing report conducted by a third-party testing institutionIL-1 levelsIL-1 concentration decrease rate(%)dexamethasoneEffeMIX-HappyCalm inhibits IL-1 much better than dexamethasoneEffeMIX-HappyCalmInhibits NF-B：IL-6The dat

5、a is from a testing report conducted by a third-party testing institutionIL-6 levelsIL-6 decrease rate(%)dexamethasoneEffeMIX-HappyCalm Significantly inhibits IL-6EffeMIX-HappyCalmInhibits NF-B：PGE2The data is from a testing report conducted by a third-party testing institutionPGE2 levelsPGE2 concen

6、tration decrease rate(%)dexamethasoneEffeMIX-HappyCalm Remarkably inhibits PGE2EffeMIX-HappyCalmInhibits Histamine H1 ReceptorsIC50：0.3563 ppmThe data is from a testing report conducted by a third-party testing institutionMast cells release histamineHistamineHistamine H1 ReceptorsIncrease the permea