这是你的重生——千载难逢的机会：当日历上显示90岁时再次成为40岁.pdf

1、Presented by:2024 Longevity SummitMichael Roizen,MD,FACPChief Wellness Officer EmeritusCleveland ClinicThis Is YOUR Do-Over :The Opportunity of a Lifetimeto be 40 again whenthe Calendar says 90Jan 26,2024Michael Roizen,MD,FACP Chief Wellness Officer Emeritus,Cleveland Clinic Professor,Cleveland Clin

2、ic Lerner College of Medicine at Case Western Reserve UniversityChief Visionary,LongevityPThe Human Genome Projects:Expected 300,000 genes based on amt of DNA in nucleus Found of 22,500 genes only 1500 or so were on or producing proteins at any one timeWhat Was Rest of DNA?It was found 7 years later

3、 to be switches that controlled which of your genes were on and producing its protein or were off.By age 18,your choices control about 80%-93%of which genes are on or off:You Genes Make Your ProteinsThose Proteins Make You&Your Health etc.You Can Control Your Genes That is Why You Can Have a Do-Over

4、 The Human Genome Projects:Expected 300,000 genes based on amt of DNA in nucleus Found of 22,500 genes only 1500 or so were on or producing proteins at any one timeWhat Was Rest of DNA?It was found 7 years later to be switches that controlled which of your genes were on and producing its protein or

5、were off.By age 18,your choices control about 80%-93%of which genes are on or off:Stress Management Changes Which of Your Genes Are On Ornish et al PNAS 2008DIET AND LIFESTYLE CHANGE GENE EXPRESSIONYou Can ControlYour Genetic Inheritance-1 All genes do is make proteins or watch other genes Which gen

6、es are On or Off?Its largely under YOUR control!When you stress your muscles,they turn on a gene that produces the small protein Irisin Irisin goes to the brain and causes increases in Brain Derived Neurotrophic Growth Factor(BDNF)BDNF Increases your hippocampal size and memory functioning You are a