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益普索:2025从隐性流行病到可量化价值:卫生系统视角下的阿尔茨海默病重审研究报告(中译版)(15页).pdf

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1、FROM SILENT EPIDEMIC FROM SILENT EPIDEMIC TO MEASURABLE VALUE TO MEASURABLE VALUE RETHINKING ALZHEIMERS THROUGH A HEALTH SYSTEMS LENS Louise HoggDirectorMarket Access and HEORAPACIpsos|2025|all rightsreserved2FROM SILENT EPIDEMIC TO MEASURABLE VALUE:RETHINKING ALZHEIMERS THROUGH A HEALTH SYSTEMS LEN

2、SExecutiveExecutiveSummarySummaryAlzheimers Disease(AD)is often perceived through a narrow clinical or caregiving lens,largely focused on late-stage symptoms and palliative support.However,this view fails to capture the broader,system-wide implications of a disease that is becoming one of the most p

3、rofound public health challenges of the 21stcentury.As populations age globally,AD functions as a stress test for health systems,exposing critical gaps in infrastructure,financing,health technology assessment(HTA),and equity.Global dementia prevalence is projectedto triple from 55 million in 2019 to

4、 152 million by 2050,with costs expected to roughly double from USD 1.3 trillion in 2019 by 2030(WHO,2021).This white paper reframes AD as not only a neurodegenerative condition but also a health system multiplier,affecting cost structures,diagnostic pathways,workforce needs,and social care delivery

5、.We explore how real-world evidence(RWE)and health economics and outcomes research(HEOR)must evolve to reflect this complexity and outline strategic recommendations for improved access,payer engagement,and policy alignment.By leveraging digital tools,rethinking traditional value frameworks,and embed

6、ding equity into every stage of evidence generation and access planning,we can move from managing decline to enabling resilience.Alzheimers is not merely a clinical diagnosis.It is a signal of systemic strain,but also of opportunity for cross-sectoral innovation.Alzheimers is not merely a clinical d

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根据《通过卫生系统视角重新思考阿尔茨海默病》白皮书,以下为全文关键点: 1. 阿尔茨海默病(AD)不仅是神经退行性疾病,也是卫生系统风险放大器,影响成本结构、诊断途径、劳动力需求和护理服务。 2. 全球痴呆症患病率预计到2050年将增至1.52亿,成本预计到2030年将翻一番,达到2.6万亿美元。 3. AD产生大量间接成本,如住院、护理机构费用、生产力损失和护理者健康问题,这些在卫生技术评估和政策对话中往往被忽视。 4. AD诊断不足,尤其是在早期阶段,导致干预机会减少。 5. 数字工具如自然语言处理、步态传感器和认知可穿戴设备正在改变这一格局,提供早期筛查和预防机会。 6. HEOR模型通常假设普遍的访问和参与,但未考虑社会背景和文化差异。 7. AD诊断、治疗和支持结构存在不平等,例如,非裔美国人患病的风险是白人的两倍。 8. 疾病修饰疗法(DMTs)的出现标志着AD管理的新时代,但需要复杂的生态系统,包括诊断、监测和劳动力准备。 9. 市场准入团队需要探索新的融资选项,实施试点项目,并重新思考市场准入策略。
系统挑战与机遇" 阿尔茨海默的隐形危机" 阿尔茨海默的未来之路"
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