益普索：2025从隐性流行病到可量化价值：卫生系统视角下的阿尔茨海默病重审研究报告（英文版）（15页）.pdf

1、FROM SILENT EPIDEMIC FROM SILENT EPIDEMIC TO MEASURABLE VALUE TO MEASURABLE VALUE RETHINKING ALZHEIMERS THROUGH A HEALTH SYSTEMS LENS Louise HoggDirectorMarket Access and HEORAPACIpsos|2025|all rightsreserved2FROM SILENT EPIDEMIC TO MEASURABLE VALUE:RETHINKING ALZHEIMERS THROUGH A HEALTH SYSTEMS LEN

2、SExecutiveExecutiveSummarySummaryAlzheimers Disease(AD)is often perceived through a narrow clinical or caregiving lens,largely focused on late-stage symptoms and palliative support.However,this view fails to capture the broader,system-wide implications of a disease that is becoming one of the most p

3、rofound public health challenges of the 21stcentury.As populations age globally,AD functions as a stress test for health systems,exposing critical gaps in infrastructure,financing,health technology assessment(HTA),and equity.Global dementia prevalence is projectedto triple from 55 million in 2019 to

4、 152 million by 2050,with costs expected to roughly double from USD 1.3 trillion in 2019 by 2030(WHO,2021).This white paper reframes AD as not only a neurodegenerative condition but also a health system multiplier,affecting cost structures,diagnostic pathways,workforce needs,and social care delivery

5、.We explore how real-world evidence(RWE)and health economics and outcomes research(HEOR)must evolve to reflect this complexity and outline strategic recommendations for improved access,payer engagement,and policy alignment.By leveraging digital tools,rethinking traditional value frameworks,and embed

6、ding equity into every stage of evidence generation and access planning,we can move from managing decline to enabling resilience.Alzheimers is not merely a clinical diagnosis.It is a signal of systemic strain,but also of opportunity for cross-sectoral innovation.Alzheimers is not merely a clinical d