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艾昆纬:深度洞察:2025亚太地区肥胖症临床试验潜力挖掘白皮书(中译版)(23页).pdf

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1、White PaperUncovering Insights:Tapping into APACs Potential for Obesity Clinical Trials A Survey Across Ten Asia Pacific CountriesCECILIA SISON,MD,FPCP,FPSG,Medical Director,Medical Science and Strategy,Asia ENA LYN ANG,MD,FPCP,FPSG,Medical Director,Medical Science and Strategy,Asia CHARU GAUTAM,MBB

2、S,MD,DNB,Senior Medical Director,Medical Science and Strategy,Asia SUJATA ROUTRAY,Clinical Planning Analyst,IQVIA APAC R&DSTable of contentsIntroduction 1Global status of obesity trials 2Objectives 2Methodology 2Results 4Investigator credentials and experience 4Epidemiology 4Patient pathway 5Diagnos

3、is 5Management and treatment 7Clinical trial experience of participating investigators 9Discussion 9Conclusion 15Disclosure 15Acknowledgment 15References 16About the authors 20 |1Obesity has become a global health problem.The global prevalence of obesity,defined as a body mass index(BMI)25kg/m,is pr

4、edicted to rise from 14%to 24%in 2020 and 2035,respectively.It is estimated that almost 2 billion will be affected by 2035.1In the Asia Pacific(APAC)region,obesity has also become a major public health concern with increasing prevalence rates.Australia has a high obesity prevalence of 31.3%based on

5、an Australian National Health Survey in 201718.2 It is similar in New Zealand at 32.5%.3 In India,the prevalence of obesity is approximately 14%using a BMI cut-off for the Asian population(27.5 kg/m2).4 In South Korea,the overall prevalence of obesity(BMI 25 kg/m2)increased from 30.2%in 2012 to 38.4

6、%in 2021,a 1.27-fold increase in 9 years.5 In Pakistan,World Health Organization(WHO)data indicates that 43.9%of the population is obese,and when Asian BMI cutoffs are applied,the prevalence is higher at 58.1%.6Among countries in Southeast Asia,Malaysia has the highest obesity prevalence rate of 33.

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根据文章内容,以下是关键点的概括: 1. 肥胖已成为亚太地区的主要公共卫生问题,不同国家的肥胖患病率在14%至58.1%之间。 2. 肥胖患者最常见的并发症包括糖尿病、高血压和血脂异常。 3. 诊断肥胖主要使用BMI,但亚太地区部分国家采用较低的BMI切点。 4. 肥胖治疗以生活方式干预为基础,药物作为辅助治疗,亚太地区部分国家推荐在较低的BMI水平开始药物治疗。 5. 参与调查的亚太地区研究者具有丰富的肥胖管理经验,对肥胖临床试验表现出浓厚兴趣。 6. 亚太地区肥胖患病率上升,研究者经验丰富,患者群体庞大,为肥胖临床试验提供了良好的环境。
APAC肥胖流行病学概况 APAC肥胖诊断与治疗现状 APAC肥胖临床试验前景
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