Anallerg®-Synyouth®：夜猫子肌肤的一体化护理——同步肌肤节律.pdf

1、Zandra Zhang，Director of MarketingShanghai CoachchemBangkok,2024.11.05Rhythm of Skin01What is“Biological Clock”？nPredict and adapt to normal biological rhythms.nSynchronize with the day-night rhythm,following a 24-hour cycle.nActivated by sunlight.nA daily cycle in every living beings.Increased bloo

2、d flowStrongest TWELMore permeableBarrier WeakensSecretion and proliferationROS Best moisturizingHighest oil secretionLower pHBarrier is strengthenedDNA damageROS Oxidative stressProtection RepairDNA damage repairThere is evidence for an active circadian clock in all cell types of the skin,and it is

3、 highly likely that distinct functions are modulated in different cell types.It is also known that circadian clock activity in skin is coordinated by the suprachiasmatic nucleus,presumably through neuronal and hormonal mediatorsJ Biol Rhythmsn All cells have biological clock.How about our skin?nThe

4、rhythms are controlled by the central clock system in the brain.nClock-related genes regulate skin.nDifferent skin functions in day and night.n Stable structure,changing functions.Bioclock GenesClockPerBmal1Cry24-hour24-hourOilier and acne-proneImbalance of oil and moistureDryness,itching,and peelin

5、gSkin barrier weakensPainful and redInflammation and SensitivityRough and tired-lookingMetabolism slow downWrinkledCells cannot repair and renew24-hour periodRhythm cannot be maintainedDisrupted rhythmDaily Mail,17 May 20152 Hours Less Sleep Per Night5 DaysDisrupted rhythmAnallerg-Synyouth02Regulati

6、ng the clock genes-Bmal1Synyouth can synchronize Bmal1 genes with natural rhythm0 mg/mLSynyouth10 mg/mLSynyouth5 mg/mLSynyouth2.5 mg/mLRegulating the clock genes-Per10 mg/mL10 mg/mL5 mg/mL2.5 mg/mLSynyouth can synchronize Per1 genes with natural rhythmInhibiting glycationl Removes AGEs(Advanced Glyc