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CITELINE:制药研发年度回顾白皮书2023(英文版)(52页).pdf

上传人: AG 编号:611613 2023-04-01 52页 14.52MB

1、Pharma R&D Annual Review 2023by Ian Lloyd,Senior Director,Pharmaprojects at CitelineWhite PaperApril 2023Reimagining the futureone chapter at a timeWelcome to Pharmaprojects 2023 review of trends in pharmaceutical R&D.For over 30 years now,Ive been taking an annual look at the evolution of pharma R&

2、D,and in this article,Ill examine the state of play at the start of 2023.Well assess industry trends by examining the pipeline by company,therapeutic area,disease,target,and drug type,using data from primarily Pharmaprojects,part of the Citeline suite of products,which has been tracking global drug

3、development since 1980.This report will be followed up by our annual supplement reviewing the New Active Substance launches for the year just passed.But here,well tell the story of pharma R&D as it is today:an epic tale,with a rich cast of characters and a global scope,and no doubt a number of unexp

4、ected plot twists.Hopefully,it will be a real page-turner!Regular readers of this report(which has been running since 1993,so is presented here in its 31st edition)will know that in recent years,Ive threaded a different theme through each edition,to highlight points,to draw analogies,and to add a li

5、ttle character into what could otherwise be a rather lengthy narrative through a potentially dreary parade of statistics,charts,and tables.Themes selected so far have included astronomy,movies,the natural world,music,food and drink,science fiction,and,last year,travel.This year,I decided to make a f

6、ew nods to the world of literature and books to help illustrate my points.Storytelling is as old as humanity itself,and fiction has always been used as a proxy to help us to understand the real world.The best literature enlightens,thrills,amuses,and engages the reader.Im certainly no Shakespeare,but

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本文是PharmaProjects的2023年药物研发年度回顾报告,由Citeline的高级总监Ian Lloyd撰写。报告通过类比小说的方式,将药物研发比作一部史诗般的故事,分析了2023年药物研发的现状和趋势。 主要内容包括: 1. 2023年药物研发管线总规模达到21,292种药物,比2022年增长了5.89%,是历史新高。 2. 管线增长主要集中在临床前和临床早期阶段,但平均药物研发周期和成本均有所上升,导致投资回报率下降。 3. 肿瘤学继续是药物研发的重点领域,占所有药物的39.8%。COVID-19相关药物研发有所放缓。 4. 罕见病药物研发持续增长,2022年有718种罕见病被药物研发项目关注。 5. 主要制药公司如罗氏、诺华、辉瑞等在药物研发管线中占据重要地位,但所占比例逐年下降。 6. 中国制药公司的研发管线增长迅速,2022年有1,457种药物处于研发中,仅次于美国。 7. 报告预测,2023年药物研发领域的并购活动将有所增加。
2023年药物研发管线增长趋势如何? 哪些疾病领域最受药物研发公司关注? 新冠疫情对药物研发产生了哪些影响?
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