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主题演讲:引领早期职业发展之路重点关注肾癌领域.pdf

上传人: 明**** 编号:1012393 2025-12-21 30页 4.55MB

1、Alt:Metabolizing and adapting in a complex cancer environmentW.Kimryn Rathmell Kimryn RathmellKeynote:Leading the Way in Fostering Early Careers with a Focus on Kidney CancerConflict of Interest DisclosuresConflict of Interest DisclosuresI hereby declare:That I do not conduct activities that would i

2、nvolve a conflict of interest with CME-accreditable training,but that in the past 2(two)years I have received the funding listed below from the following sources:Grant/Research support from(spouse):Incyte Pharmaceuticals Consulting/Honoraria(spouse):Roche,Pfizer,Caribou Advisory Board(spouse):Sitryx

3、Conflict of Commitment DisclosuresConflict of Commitment Disclosures-Academic ActivismAcademic Activism-I hereby declare:That I am committed to ensuring that we have a robust pipeline of students seeking careers in STEM,that we foster curiosity,discovery,and rigor in the realm of health care,and tha

4、t we support research that advances human health:Scientific Advisory Boards(past):NCI Board of Scientific Advisors,William Guy Forbeck Foundation Training Grants(past):VCORCDP K12,VIMO Research Training Program T32,serving on a variety of External Advisory Committees(MSKCC,MDACC,UPenn,UChicago,MUSC,

5、Emory)Physician Scientist Support Grants(past):Burroughs Wellcome Foundation,Damon Runyon Foundation Award Panels:Paul Marks Prize(chair),FNIH Paul-Gallin Trailblazer Prize Awards Panels(past):Korsmeyer Award,Seldin-Smith Award,Harrington Prize,AACR Daniel Von Hoff Award,ASCO Special Awards Funding

6、for Kidney Cancer(past):Department of Defense Kidney Cancer Research Program,Kidney Cancer Association,VHL Alliance,KC-CURE Sponsored Programs for Early STEM focus:Aspirnaut Program,Meharry Medical Student Scientific Immersion Program,UNI Rathmell2 Endowed Research Scholarship Fund Writing:Thought p

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根据报告的内容,本文主要讨论了癌症研究,特别是肾脏癌(ccRCC)的代谢和适应性,以及如何培养年轻科学家。以下是关键点: 1. ccRCC肿瘤代谢与转移潜力紧密相关,VHL基因缺失和HIF表达是关键因素。 2. 研究发现,ccRCC中ccB表达与更高的FDG摄取相关,可能通过NDUFA4L2介导。 3. 需要更多年轻科学家投身于癌症研究,并鼓励创新和跨学科合作。 4. 建议导师挑战年轻科学家,创造机会,奖励创新,并给予灵活性。 5. 机构应倾听、适应、重视年轻科学家,并培养强大的导师团队。 6. 全体合作,重塑科学工作队伍,推动癌症研究发展。
颠覆性突破?" 早期职业发展之道?" 如何打破资金壁垒?"
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