Projected Global Burden of Pediatric Cancer： 2020–2050-行业数据

worldwide are concentrated in Asia and Africa. diagnosis, resulting in more advanced disease at presentation challenges in data collection and reporting, current estimates and, consequently, markedly lower survival. As a result, Beyond the total burden, the types of cancers affecting The economic burden on families is also profound. Bangladesh illustrates a challenge common to many LICs and LMICs. the United States. Globally, the most frequently diagnosed An estimated 9,000 pediatric cancer cases occur annually pediatric cancers are leukemias, central nervous system in Bangladesh; however, only about 5 percent of children receive care in a hospital setting (617). This gap is driven by in incidence and outcomes, largely influenced by differences costs faced by families. In many LMICs, families spend more in demographics, health care infrastructure, socioeconomic than their total monthly income on cancer treatment, often development, and timely access to diagnosis, treatment, and without financial assistance (e.g., subsidized health insurance) supportive care. For example, although treatment advances in (614,617). Even when treatment costs are subsidized, the survival, these gains have not been realized uniformly around the globe. Although 5-year survival rates for pediatric cancers approach 80 percent in HICs, survival rates for these cancers in LICs and LMICs remain below 30 percent (610). Several system-level factors contribute to these disparities. In many low-resource settings, the availability of WHO's exacerbate disparities. For example, RB in LMICs is usually Solutions, p. 138). A global survey of LICs and LMICs the removal of the eye from the socket (620). However, the treat their disease (611). In addition, insufficient pediatric result in underdiagnosis, misdiagnosis, and delays in care. a clear example of this disparity, whereby 30 percent to 40 OF NEARLY $2 BILLION BETWEEN 2020 AND 2050. advanced stage, compared to only 2 percent to 5 percent in developed countries(612). The lack of diagnostic infrastructure