信迪利单抗解离速率低-行业数据

信迪利单抗解离速率低

抗体与靶点的结合作用包含结合和解离两个相反的动态过程。解离速率越快，PD-1 越可能重新与肿瘤细胞上的 PD-L1 重新结合，触发免疫抑制，造成肿瘤细胞逃逸。与 Keytruda相比，信迪利单抗自 PD-1 解离的速率更低，有效延长其与 PD-1 结合的持续时间，实现更强劲、持久的免疫逃逸抑制作用。

行业数据

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