加拿大卫生研究院的临床试验.pptx

1、Clinical Trials Ontario ConferenceNovember 6,2024,Updates-Clinical Trials at the Canadian Institutes of Health Research,Building CIHRs clinical trials program,Priority E:Integrate Evidence in Health DecisionsE.3.3 Enhance Canadas capacity to fund,conduct and use clinical trials by strengthening high

2、ly qualified personnel,clinical trials environments and research investmentsPriority A:Advance Research Excellence in All Its DiversityA.3.3 Promote monitor and report on CIHR-funded researcher compliance with the WHO statement of Public Disclosure of Results from Clinical Trials,Clinical Trials Fun

3、d:now fully allocated,Three inter-related building blocks form the CIHR Clinical Trials Fund,Applying CIHRs research excellence framework to clinical trials,we have published best practices recommendations,including:Inclusion of populations and justifications of any exclusionsEquity,diversity,inclus

4、ion and accessibility considerations in trial planningDiversity in data describing the trial populations in results and providing disaggregated results where valid to do soPatient-oriented research approaches in all stages of trial design and implementationKnowledge mobilization planningOpen science

5、 enabling secondary use of data,disclosure of protocolsUse of standardized approaches such as core outcome sets to improve comparabilityDeveloping and supporting diverse research teamsUsing available processes to improve clinical trial efficiency,including streamlined REB and contracting processesIm

6、plementation of these elements as mandatory application requirements would require the development of additional guidance for applicants and reviewers,as well as ongoing resources to monitor and evaluate.,Policy development building better clinical trials,In October 2020,CIHR signed onto the WHO Joi