1、MARCH2026Measuring the Estimated Size of the U.S.Pharmaceutical Market on a Net Manufacturer Price BasisTECHNICAL NOTEThe IQVIA Institute for Human Data Science has been estimating the size and growth of the U.S.pharmaceutical market at net manufacturer prices for 14 years.During this time,the marke
2、t has seen significant change and has become more complex;however,the methods used for estimating spending at net manufacturer prices have largely remained unchanged.To better inform stakeholders and policy discussions,the IQVIA Institute has recently undertaken an extensive review and analysis of c
3、urrent market and measurement dynamics to develop an improved approach,utilizing best available publicly disclosed information combined with proprietary IQVIA databases,to estimate total prescription medicine spending at net manufacturer prices.This new method will provide more accurate and transpar
4、ent estimates of the size and growth of spending on prescription medicines in the U.S.and will better inform discussions and decision-making by all stakeholders.This technical note from the IQVIA Institute for Human Data Science is intended to provide an update on methodologies for research on medic
5、ine spending published in our trend reports covering the use of medicines in the U.S.Updated spending estimates for 20152024 provide a comparison to prior IQVIA Institute publications and estimates.Estimates based on the most up-to-date data,including 2025,will be provided in our forthcoming report
6、on Use of Medicines in the U.S.to be published in April 2026.Find Out MoreIf you wish to receive future reports from the IQVIA Institute for Human Data Science or join our mailing list,visit iqviainstitute.org.MURRAY AITKENExecutive Director IQVIA Institute for Human Data ScienceIntroductionMeasurin