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Citeline:2022年度临床试验概述白皮书(中译版)(20页).pdf

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1、2022 Clinical Trials RoundupOctober 2023White PaperHeidi ChenAssociate Director,Research&Commercial Services2October 2023 Copyright 2023 Citeline,a Norstella company.(Unauthorized photocopying prohibited).2022 Clinical Trials Roundup1.Citeline(2022)2021 Clinical Trials Roundup:Clinical Trials Resili

2、ence After Pandemic Disruptions.2.The data snapshot dates for full-year activity are June 26,2023;June 23,2022;June 14,2021;June 12,2020;June 5,2019;June 6,2018;and July 6,2017.Due to delays in reporting of trial activity,counts for prior years will have likely grown since the original data snapshot

3、 date.Last year we remarked on the resilience and return of clinical trial momentum post-pandemic,where we saw a 6%growth of total trials(22%excluding COVID-19 trials)in 2021.1 One year later,the roller coaster resumes as the healthcare industry continues to be influenced by the global economy and p

4、olitical climate.Big headline events the Inflation Reduction Act,the ongoing Russo-Ukrainian war,harsh funding cuts and divestments in the biopharma sector,and stalled economic growth in China are just a few headwinds the healthcare industry braved in 2022.As the world picks up the pace to rebuild m

5、omentum and put the pandemic behind it,navigating through the evolving regulatory guidance and market dynamics calls for endurance and perseverance.As with each edition of our Clinical Trials Roundup,we focus on an overview of the Phase IIII clinical trials that initiated in the prior calendar year(

6、2022)across all therapeutic areas comprehensively covered by Trialtrove,as well as in-depth analyses into the key diseases,players,and geographies that impact the pharmaceutical industry.We will also look at any lingering effect of the pandemic,recovery,and challenges of adapting to the new equilibr

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本文主要内容概括如下: 1. 2022年,全球临床试验数量较2021年有所下降,共9,104项,比2021年下降了12.5%。这是自2016年以来首次出现下降趋势。 2. 排除COVID-19相关试验后,2022年临床试验数量比2021年下降了6%,表明临床试验数量恢复到疫情前水平。 3. 2022年,中国和美国仍然是临床试验数量最多的国家,分别有3,405项和2,876项。 4. 2022年,肿瘤学、感染病学、中枢神经系统疾病、代谢/内分泌疾病、自身免疫/炎症性疾病、眼科疾病、泌尿系统疾病等治疗领域的临床试验数量都有所下降。 5. 2022年,辉瑞、阿斯利康、罗氏、默克和强生等大型制药公司仍然是临床试验的主要赞助商。 6. 2022年,临床试验的地理分布相对稳定,中国和美国在所有治疗领域中均占据前两位。 7. 文章指出,临床试验数量下降可能与全球经济和政治环境的变化有关,包括通货膨胀减少法案、俄罗斯与乌克兰战争、中国经济的放缓等。 8. 文章还提到,临床试验行业正在探索使用去中心化临床试验、真实世界数据和人工智能等新技术来提高临床试验的效率和包容性。
2022年临床试验数量为何下降? 哪些疾病在2022年临床试验中占据主导地位? 2022年哪些地区临床试验数量最多?
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