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达尔西利国内管线情况
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所属报告：
恒瑞医药-公司研究报告-创新变革迎拐点蝶变新生向未来-230404（111页）.pdf
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达尔西利销售额峰值有望达23亿元
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行业数据
2023-04-12
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达尔西利联合内分泌辅助治疗HR+/HER2-BCIII期临床研究设计
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行业数据
2023-03-15
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行业数据
2023-03-15
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行业数据
2023-01-13
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达尔西利销售预测
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2022-11-04
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达尔西利与其他CDK4/6疗效对比
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行业数据
2022-11-04
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达尔西利+来曲唑/阿那曲唑mBCHR+/HER2-1L适应症的临床数据（LBA16/DAWNA-2）
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行业数据
2022-10-08
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达尔西利临床进度
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行业数据
2022-10-08
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达尔西利国内竞争格局（截至2022年6月）
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行业数据
2022-09-30
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达尔西利的销售预测
5aW955qE77yM5Lul5LiL5piv5oKo5Zu+54mH5Lit55qE5pWw5o2u6KGo5qC85ZKM6LWE5paZ5p2l5rqQ77yaCgp8IOWNleS9jSB8IDIwMjJFIHwgMjAyM0UgfCAyMDI0RSB8IDIwMjVFIHwgMjAyNkUgfAp8LS0tLS0tfC0tLS0tLS18LS0tLS0tLXwtLS0tLS0tfC0tLS0tLS18LS0tLS0tLXwKfCDmlrDlop7mgqPogIXmlbDph48gKOS4hykgfCA0MC45ICB8IDQxLjEgIHwgNDEuMyAgfCA0MS41ICB8IDQxLjcgIHwKfCB5b3kgKCUpIHwgMC41JSAgfCAwLjUlICB8IDAuNSUgIHwgMC41JSAgfCAwLjUlICB8CnwgSFIrL0hFUjItIOavlOS+iyAoJSkgfCA3MC4wJSB8IDcwLjAlIHwgNzAuMCUgfCA3MC4wJSB8IDcwLjAlIHwKfCBIUisvSEVSMi0g5oKj6ICF5pWw6YePICjkuIcpIHwgMjguNiAgfCAyOC43ICB8IDI4LjkgIHwgMjkuMCAgfCAyOS4yICB8CnwgSFIrL0hFUjItIOayu+eWl+avlOS+iyAoJSkgfCA4MCUgICB8IDgwJSAgIHwgODAlICAgfCA4MCUgICB8IDgwJSAgIHwKfCBIUisvSEVSMi0g5rK755aX5Lq65pWwICjkuIfkuropIHwgMjIuODggfCAyMi45OSB8IDIzLjExIHwgMjMuMjIgfCAyMy4zNCB8Cnwg6L6+5bCU6KW/5YipIOayu+eWl+i0ueeUqCAo5LiH5YWDL+W5tCkgfCAxNy41NSB8IDkuMDAgIHwgOS4wMCAgfCA3LjIwICB8IDcuMjAgIHwKfCBDREs0LzYg5riX6YCP546HICglKSB8IDAuMyUgIHwgNC4wJSAgfCA4LjAlICB8IDEyLjAlIHwgMTUuMCUgfAp8IENESzQvNiDnlKjoja/kurrmlbAgKOS4h+S6uikgfCAwLjA3ICB8IDAuOTIgIHwgMS44NSAgfCAyLjc5ICB8IDMuNTAgIHwKfCBDREs0LzYg6ZSA5ZSu6aKdICjkur/lhYMpIHwgMS4yMCAgfCA4LjI4ICB8IDE2LjY0IHwgMjAuMDYgfCAyNS4yMSB8CgrotYTmlpnmnaXmupDvvJroja/mmbrnvZHvvIxHTE9CQUxDQU7vvIzkuJzlkLTor4HliLjnoJTnqbbmiYA=
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行业数据
2022-09-14
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达尔西利主要临床开发适应症为激素受体（HR）阳性、人表皮生长因子受体 2（HER2）阴性乳腺癌。作为国内第一个自主研发的口服 CDK4/6 产品，达尔西利联合氟维司群在内分泌治疗耐药后的 HR+/HER2-乳腺癌患者中，显著改善 PFS，降低死亡风险，且安全性良好。结果显示，与安慰剂组相比，达尔西利组患者 PFS 显著延长（15.7 个月对 7.2 个月），降低疾病进展或死亡风险高达 58%。 无论从患者的年龄、绝经状态、是否合并内脏转移、是否接受过内分泌治疗、既往内分泌治疗线数、是否接受过挽救化疗等各方面情况衡量，与安慰剂组相比，PFS 获益均一致倾向于达尔西利组。相关研究成果在国际权威学术期刊《自然医学》（Nature Medicine，影响因子 53.44）全文发表。
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