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TELUS Health:2025年加拿大药物研发管线:私人药物保险计划机遇与挑战研究报告(英文版)(25页).pdf

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1、Drug Pipeline:What private plans need to know.2025 March 20252P.l 2025 Drug PipelineContentsIntroduction .3 Alzheimers disease .4 Plaque psoriasis .8 Whats old is new again.10 Migraine.11 Attention deficit hyperactivity disorder.12 Macular edema due to uveitis.12Weight management .13 2025 new drug p

2、ipeline summary.15 Generics .17 Biosimilars .20 Conclusion .23 3P.l 2025 Drug PipelineIntroductionVicky Lee,RPh,BScPhm,MMI,BSc.HonsDirector,Pharmacy Consulting&Professional Services Payor Solutions,TELUS HealthAt the start of this year,approximately 17,700 drugs were under development in Canada,down

3、 slightly from the 18,000 reported at the start of 2024 but still well ahead of the 16,200 reported in 2023.About one in six this year(2,900)are in the final,phase-3 stage of development.From this large pool of potential new medications,fewer than 200 will make it to Health Canada for regulatory rev

4、iew.Health Canada is currently evaluating 159 submissions,up somewhat from the previous two years at this point(120 in 2024 and 123 in 2023)and comparable to 2022(142)and 2021(150).Just over half of this years submissions(58 per cent)are for new drugs,consistent with the previous four years,and the

5、remaining submissions are for new or expanded indications for drugs already on the market.The 2025 Drug Pipeline report takes a closer look at 10 new drugs to consider their anticipated impact on private drug plans and workplace productivity,including two breakthrough medications for Alzheimers dise

6、ase.Other new medications of interest to plan sponsors are in the areas of psoriasis,migraine and attention deficit hyperactivity disorder.The report also provides an update on three upcoming drugs for weight management,although none have yet been submitted to Health Canada for review.The 2025 editi

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本文主要介绍了2025年加拿大药物管道报告,重点关注了10种新药及其对私人药物计划的影响。 1. 阿尔茨海默病:两种新药(Leqembi和Kisunla)正在等待加拿大卫生部的审批,这两种药物可以减缓早期阿尔茨海默病的进展。 2. 银屑病:Vtama(tapinarof)和icotrokinra(品牌名称待定)正在研发中,这两种药物为银屑病提供了新的治疗选择。 3. 偏头痛:Elyxyb(celecoxib)是一种新的急性偏头痛治疗药物,正在等待加拿大卫生部的审批。 4. 注意力缺陷多动障碍(ADHD):Jornay PM(methylphenidate)是一种新的ADHD治疗药物,已于2024年11月获得加拿大卫生部的批准。 5. 葡萄膜炎引起的黄斑水肿:Xipere(triamcinolone acetonide)是一种新的眼部疾病治疗药物,正在等待加拿大卫生部的审批。 6. 体重管理:CagriSema(semaglutide-cagrilintide)和retatrutide(品牌名称待定)正在研发中,这两种药物为体重管理提供了新的治疗选择。 7. 仿制药和生物仿制药:预计将有超过30种仿制药和生物仿制药上市,这将降低药物计划的支出。 综上所述,2025年药物管道报告关注了多种新药及其对私人药物计划的影响,包括阿尔茨海默病、银屑病、偏头痛、ADHD、葡萄膜炎引起的黄斑水肿和体重管理等疾病。同时,仿制药和生物仿制药的上市也将降低药物计划的支出。
阿尔茨海默病新药Kisunla和Leqembi对私人药物计划有何影响? 非类固醇类外用治疗Vtama对银屑病有何疗效? 糖尿病药物的仿制药何时上市,对私人药物计划有何影响?
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