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Harris Williams:2023Q1外包制药服务和制药技术报告(英文版)(18页).pdf

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1、Outsourced Pharma Services&Pharma Tech Sector Update Harris Williams|Q1 2023Outsourced Pharma Services and Pharma Tech|Q1 2023Biopharmaceutical companies increasingly rely on technology and service vendors to accelerate research and development and time to market as well as optimize commercial succe

2、ss of therapies.Outsourced Pharma Services and Pharma Tech:Observations and Key TrendsDiscoveryResearch&DevelopmentLaunchPost-Launch/In-MarketAs target populations reduce in size and cost of commercialization increases,pharma is increasingly focused on solutions that keep patients engaged and adhere

3、nt to their course of care.Targeting AdherenceThe indications that pharma is targeting for new therapies are becoming increasingly complex and focused,resulting in higher overall discovery and development costs.These therapeutics,which are more frequently large molecule,are targeting significantly s

4、maller,more complex patient populations,making it more difficult and costly to recruit and retain patients in clinical trials.Increasing Complexity and Cost of R&D ProcessReal-world evidence(RWE)and data is playing an increasingly crucial role in clinical and commercialization stages of development,

5、helping pharma manufacturers quickly and effectively bring therapies to market and identify and prove out additional indications.Focus on RWEAs pharmaceutical products become increasingly specialized and more costly,payors are pushing back and requiring robust outcomes evidence to support reimbursem

6、ent.Challenges With PayorsLegacy Commercialization Approaches Are No Longer EffectiveAs many blockbuster pharmaceuticals approach the end of their patented life and face generic competition,pharma manufacturers are targeting growth through niche opportunities with smaller addressable markets.Effecti

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本文主要讨论了2023年第一季度制药服务和制药技术行业的更新。主要内容包括: 1. 生物制药公司越来越依赖技术和服务供应商来加速研究和开发,缩短上市时间,以及优化疗法的商业成功。 2. 制药公司正在关注保持患者参与度和依从性的解决方案,因为目标人群减少,商业化成本增加。 3. 制药公司正在开发针对复杂和专注的适应症的疗法,这导致更高的整体发现和开发成本。 4. 真实世界证据(RWE)和数据在临床和商业化阶段发挥着越来越重要的作用,帮助制药制造商快速有效地将疗法推向市场。 5. 随着许多重磅药物接近专利期结束并面临仿制药竞争,制药制造商正在通过针对较小目标市场的利基机会来寻求增长。 6. 由于全球供应链问题,依赖专门网络将成品推向市场的制药公司受到影响。 7. 制药公司正在寻找增强供应链可见性或将制造业务转移到国内的解决方案。 8. 随着开发成本的增加,制药公司正在关注技术和专业化的临床试验网站,以创造效率、节省成本,并允许制药公司管理狭窄的患者人群。 9. 随着COVID-19加速远程和分散测试的步伐,以及患者在哪里接受护理的方式,有效地管理试验和信息传递需要技术解决方案和服务供应商。 10. 制药公司正在寻求优化开发和商业化生命周期的每个部分的服务和技术合作伙伴,以加快上市时间并简化商业化。
生物制药公司如何利用技术和外包服务加速研发和上市时间? 针对复杂适应症的药物研发如何提高患者依从性? 制药公司如何利用真实世界证据(RWE)加快药物上市和证明额外适应症?
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